Best Supplements for Heart Health: What Lowers Risk Factors
Psyllium and plant sterols lower LDL; omega-3s lower triglycerides; CoQ10 may help heart failure. Multivitamins don't prevent heart disease. See doses.
By the editorial team · Updated Oct 14, 2026 · 3 sources cited
The best supplements for heart health improve specific risk factors. Psyllium fiber and plant sterols lower LDL cholesterol, omega-3s lower high triglycerides, and CoQ10 shows promise as an add-on in heart failure. Multivitamins, vitamin D and vitamin E haven't prevented heart attacks in large trials. Statins and blood pressure medicines remain the proven tools.
Evidence-ranked options
| Supplement | Evidence | Typical dose | Notes |
|---|---|---|---|
| Psyllium fiber | A | 7–10 g a day | Lowers LDL cholesterol. |
| Plant sterols/stanols | A | 1.5–3 g a day with meals | Lower LDL by about 6–12% in meta-analyses. |
| Omega-3 (EPA + DHA) | A | 2–4 g a day for high triglycerides, with a doctor | Large triglyceride reductions; general prevention evidence is mixed. |
| CoQ10 | B | 100–300 mg a day | Add-on in heart failure; interacts with warfarin. |
| Multivitamins | D | Not for heart disease prevention | USPSTF found insufficient evidence of benefit. |
A: strong · B: moderate · C: limited or mixed · D: good evidence of no benefit. See the evidence database.
Heart health basics
Know your numbers (blood pressure, LDL, blood sugar), stay active, don't smoke, and follow your doctor's treatment plan. Related guides: blood pressure and cholesterol.
Ingredient guides
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Frequently asked questions
Can supplements replace statins?
No. Statins reduce heart attacks and deaths in large trials; supplements haven't shown that. Red yeast rice contains a statin-like compound and shouldn't be combined with statins.
Is fish oil good for the heart?
It lowers triglycerides. For people without heart disease, benefits in large trials were mixed, and high doses slightly raise the risk of atrial fibrillation.
Sources
Educational content, not medical advice. Read our medical disclaimer.