Red Yeast Rice Supplements: Benefits, Dosage and Safety

Summary

Red yeast rice supplements lower LDL cholesterol because they can contain monacolin K, chemically identical to the statin lovastatin. That also means statin-like side effects. Products vary hugely in monacolin content and some contain a kidney toxin called citrinin.

Evidence at a glance

UseGradeWhat the research shows
Lowering LDL cholesterolBWorks when monacolin K is present.

A: strong, consistent human evidence · B: moderate · C: limited or mixed · D: good evidence of no benefit.

Red yeast rice is made by fermenting rice with a yeast used in traditional Chinese medicine.

How to take it

Use only with your doctor's knowledge, and never alongside a statin. See supplements for high cholesterol.

Safety and interactions

Muscle pain, liver problems and drug interactions are possible, as with statins.

Always tell your doctor and pharmacist about the supplements you take. Check combinations with our interaction checker.

Sources

  1. NCCIH: Red Yeast Rice

This page is for education and is not a substitute for advice from your doctor. Read our medical disclaimer.