Ashwagandha Supplements: Benefits, Side Effects and Dosage

Summary

Ashwagandha is a traditional Ayurvedic herb. Small trials suggest it can lower stress scores and may improve sleep when taken for 6โ€“8 weeks at 300โ€“600 mg a day. It's usually well tolerated, but rare liver injury has been reported, and it isn't suitable during pregnancy or for people with thyroid conditions.

Evidence at a glance

UseGradeWhat the research shows
Perceived stressBSeveral small randomized trials show lower stress scores than placebo.
Sleep qualityCSome trials show improvement; studies are small and short.
AnxietyCPromising but limited and partly industry-funded evidence.
Testosterone and fertility in menCSmall trials report increases; needs confirmation.

A: strong, consistent human evidence ยท B: moderate ยท C: limited or mixed ยท D: good evidence of no benefit.

Ashwagandha has been used in Ayurvedic medicine for centuries and is now one of the best-selling herbal supplements. It's called an "adaptogen," a term for herbs thought to help the body handle stress, though that's a traditional idea rather than a defined medical category.

What the research shows

Most human trials used root extracts for 6โ€“12 weeks in adults reporting stress. Several found lower stress and anxiety scores and, in some, lower cortisol compared with placebo. The trials are generally small and short, and some were funded by extract makers, so the evidence is promising but not definitive.

Choosing a product

  • Prefer root extracts with the withanolide content listed
  • Branded extracts such as KSM-66 and Sensoril have their own trials, at different doses
  • Look for third-party testing for purity

If you're deciding between adaptogens, see ashwagandha vs rhodiola.

Side effects and who should avoid it

Common side effects include drowsiness and stomach upset. Rare cases of liver injury have been reported; stop and see a doctor if you notice yellow skin or eyes or dark urine. Avoid it during pregnancy and breastfeeding, and talk to a doctor first if you have a thyroid or autoimmune condition, or take sedatives, thyroid medication, immunosuppressants, or diabetes or blood pressure drugs.

Sources

  1. NIH Office of Dietary Supplements: Ashwagandha Fact Sheet for Health Professionals
  2. NCCIH: Ashwagandha

This page is for education and is not a substitute for advice from your doctor. Read our medical disclaimer.

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