Soy Isoflavones Supplements: Benefits, Dosage and Safety

Summary

Soy isoflavone supplements may slightly reduce hot flashes for some women, according to NCCIH, though results vary. Eating soy foods is safe for most people. Women with a history of hormone-sensitive cancer should ask their doctor before using isoflavone supplements.

Evidence at a glance

UseGradeWhat the research shows
Menopausal hot flashesCSmall reductions in some trials.

A: strong, consistent human evidence ยท B: moderate ยท C: limited or mixed ยท D: good evidence of no benefit.

Isoflavones are plant compounds in soybeans with weak estrogen-like effects.

How to take it

Studies used 40โ€“80 mg daily for several weeks. See menopause supplements.

Safety and interactions

Mild stomach upset is possible. Long-term high-dose supplement safety is less clear.

Always tell your doctor and pharmacist about the supplements you take. Check combinations with our interaction checker.

Sources

  1. NCCIH: Soy

This page is for education and is not a substitute for advice from your doctor. Read our medical disclaimer.