Lutein and Zeaxanthin Supplements: Benefits, Dosage and Safety

Summary

Lutein and zeaxanthin supplements are carotenoids that collect in the retina. They're part of the AREDS2 formula, which slows progression of intermediate age-related macular degeneration. Evidence for preventing eye disease in people with healthy eyes is limited.

Evidence at a glance

UseGradeWhat the research shows
Slowing intermediate AMD (AREDS2 formula)APart of the formula shown to slow progression.
Preventing eye disease in healthy peopleCLimited evidence.

A: strong, consistent human evidence · B: moderate · C: limited or mixed · D: good evidence of no benefit.

Lutein and zeaxanthin filter blue light and protect the macula, the center of the retina.

How to take it

AREDS2 uses 10 mg lutein and 2 mg zeaxanthin daily. Ask your eye doctor whether it's right for you. See vision supplements.

Safety and interactions

Generally safe; high intakes can harmlessly tint skin yellow.

Always tell your doctor and pharmacist about the supplements you take. Check combinations with our interaction checker.

Sources

  1. AREDS2 Research Group. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration. JAMA. 2013

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